Avian Leukosis Virus
Eto mga kakmeyts, may nakita akong detalyadong explanation about Leukosis;
Lymphoid leukosis is the most common manifestation of the avian leukosis/sarcoma group of viruses which produces a variety of neoplastic diseases including erythroblastosis, myelocytomatosis, myeloblastosis and others.
Although not all infected animals will develop tumors, nearly every commercial flock contains infected birds, and therefore, sporadic occurrence of tumors may result. Infection occurs horizontally, from bird to bird by direct or indirect contact, or vertically, from an infected hen to her eggs as virus is shed into the albumin of the egg. In addition, vertical transmission may occur from virus incorporated in the DNA of a germ cell. Viremia in the hen is strongly associated with the transmission of virus congenitally. Enzyme immunoassays have proven efficacious in the detection of leukosis antibody and antigen.
This Enzyme Immunoassay is designed to measure the relative level of antibody to Avian Leukosis Virus (ALV) subgroups A and B in chicken serum. Antibody to subgroup E viruses, which include the endogenous leukosis viruses, is not detected.
This Enzyme Immunoassay is designed to measure the level of p27, a viral antigen common to all subgroups of Avian Leukosis Virus (ALV) in chicken serum or egg albumin. Protocols for serum and albumin samples are similar except for the type of wash solution used. Specifically, serum samples are washed with distilled/deionized water, whereas albumin samples require the use of a 20X wash concentrate.
Subgroup J Antibody
This Enzyme Immunoassay is designed to detect ALV Subgroup J antibodies in chicken serum. The test was developed as a flock-screening tool for monitoring horizontal transmission of the virus. A positive antibody test result indicates exposure to ALV-J, but may not reflect whether virus is being actively shed. Vertical transmission of ALV-J can result in immune tolerant progeny that are negative on the antibody test. A testing program for determining the ALV-J status of flocks should also include testing for the presence of viraemia and/or shedding of virus. ALV-J antibody testing of meat-type birds less that 10 weeks of age is not recommended.